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    <h1>One time workaround:</h1> <pre><code>pip install --user --install-option="--prefix=" &lt;package_name&gt; </code></pre> <p>or</p> <pre><code>python setup.py install --user --prefix= </code></pre> <p>Note that there is no text (not even whitespace) after the <code>=</code>.</p> <p>Do <em>not</em> forget the <code>--user</code> flag.</p> <h1>Installing multiple packages:</h1> <p>Create <code>~/.pydistutils.cfg</code> (or equivalent for your OS/platform) with the following contents:</p> <pre><code>[install] prefix= </code></pre> <p>Note that there is no text (not even whitespace) after the <code>=</code>.</p> <p>Then run the necessary <code>pip install --user</code> or <code>python setup.py install --user</code> commands. Do <em>not</em> forget the <code>--user</code> flag.</p> <p>Finally, remove or rename this file. Leaving this file present will cause issues when installing Python packages system-wide (i.e., without <code>--user</code>) as this user with this <code>~/.pydistutils.cfg</code>.</p> <h1>The cause of this issue</h1> <p>This appears to be an issue with both OpenSUSE and RedHat, which has lead to <a href="https://bugs.launchpad.net/virtualenv/+bug/248558">a bug in virtualenv</a> on these platforms.</p> <p>The error stems from a system-level <a href="http://docs.python.org/install/index.html#distutils-configuration-files">distutils configuration file</a> (in my case <code>/usr/lib64/python2.6/distutils/distutils.cfg</code>) where there was this</p> <pre><code>[install] prefix=/usr/local </code></pre> <p>Basically, this is equivalent to always running the install command as <code>install --prefix=/usr/local</code>. You have to override this specification using one of the techniques above.</p>
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    1. POCombine --user with --prefix error with setup.py install
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    1. COThank you very much. The empty prefix fixed my problem: pip 1.1 openSuSE 11.4.
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    2. COYou could also pass a empty --prefix= to setup.py in the command line to override the value in the system-wide distutils.cfg
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    3. COWow! This worked for me too. I received the same error when trying to install Powerline. https://powerline.readthedocs.org/en/latest/installation/osx.html#i-receive-an-importerror-when-trying-to-use-powerline-on-os-x
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