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    <p>Here is something I put together that might do what you are describing. It is quick and dirty, but it might get you going:</p> <p>I have a blank DataGridView, a combobox, and a textbox on a form. TestObject is a class that is an object with 3 string properties for testing purposes of this example.</p> <p>For ease, I initialize a generic list with a few instances of TestObject. I then manually add 3 columns to the datagridview which correspond to the 3 properties of TestObject. I then iterate through the list and manually add them to the datagridview, as well as actually storing the object in the Row's tag property as well.</p> <p>I then fill the combobox with references to the columns in the datagridview. The user will select which column she/he wants to search for, then type the text to match in the textbox.</p> <p>I then handle the textbox textchanged event to search the datagridview based on the column that is selected in the combobox and the text in the textbox. For a bigger dataset, you wouldn't want to handle the textchanged event because it would be too slow to search after every letter change. </p> <p>Without using a datatable or datasource, I can't think of any easy way to search the rows without iterating. I don't know your requirements, but I would use a bindingsource with a list or set up a datatable at a minimum. With a bindingsource you could also apply a filter and dynamically show only those results that match your search.</p> <pre><code>using System; using System.Collections.Generic; using System.Windows.Forms; namespace WindowsFormsApplication2 { public partial class Form1 : Form { public Form1() { InitializeComponent(); List&lt;TestObject&gt; objects = new List&lt;TestObject&gt; { new TestObject("1", "object1", "first"), new TestObject("2", "object2", "nada"), new TestObject("3", "object3", "Hello World!"), new TestObject("4", "object4", "last") }; dataGridView1.Columns.Add("ColID", "ID"); dataGridView1.Columns.Add("ColName", "Name"); dataGridView1.Columns.Add("ColInfo", "Info"); foreach (TestObject testObject in objects) { int row = dataGridView1.Rows.Add(); dataGridView1.Rows[row].Cells["ColID"].Value = testObject.ID; dataGridView1.Rows[row].Cells["ColName"].Value = testObject.Name; dataGridView1.Rows[row].Cells["ColInfo"].Value = testObject.Info; dataGridView1.Rows[row].Tag = testObject; } foreach (DataGridViewColumn col in dataGridView1.Columns) { comboBox1.Items.Add(col); } comboBox1.ValueMember = "HeaderText"; comboBox1.SelectedIndex = 0; } private void textBox1_TextChanged(object sender, EventArgs e) { dataGridView1.ClearSelection(); foreach (DataGridViewRow row in dataGridView1.Rows) { if (row.Cells[((DataGridViewColumn)comboBox1.SelectedItem).Name].Value == null) { continue; } if (row.Cells[((DataGridViewColumn)comboBox1.SelectedItem).Name].Value.ToString().Equals( textBox1.Text,StringComparison.InvariantCultureIgnoreCase)) { row.Selected = true; return; } } } } } public class TestObject { public TestObject(string id, string name, string info) { ID = id; Name = name; Info = info; } public string ID { get; set; } public string Info { get; set; } public string Name { get; set; } } </code></pre>
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