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I didn't believe Bittercode as he said that LINQ would outperform regex. So I did a little test just to be sure. Three examples of how to do this: <pre><code>Dim _invalidChars As Char() = New Char() {"j"c, "a"c, "n"c} Dim _textToStrip As String = "The quick brown fox jumps over the lazy dog" Private Sub btnStripInvalidCharsLINQ_Click(sender As System.Object, e As System.EventArgs) Handles btnStripInvalidCharsLINQ.Click Dim stripped As String = String.Empty Dim sw As Stopwatch = Stopwatch.StartNew For i As Integer = 0 To 10000 stripped = _textToStrip.Where(Function(c As Char) Not _invalidChars.Contains(c)).ToArray Next sw.Stop() lblStripInvalidCharsLINQ.Text = _stripped & " - in " & sw.Elapsed.TotalMilliseconds & " ms" End Sub Private Sub btnStripInvalidCharsFOR_Click(sender As System.Object, e As System.EventArgs) Handles btnStripInvalidCharsFOR.Click Dim stripped As String = String.Empty Dim sw As Stopwatch = Stopwatch.StartNew stripped = _textToStrip For i As Integer = 0 To 10000 For Each c As Char In _invalidChars stripped = stripped.Replace(c, "") Next Next sw.Stop() lblStipInvalidcharsFor.Text = stripped & " - in " & sw.Elapsed.TotalMilliseconds & " ms" End Sub Private Sub btnStripInvalidCharsREGEX_Click(sender As System.Object, e As System.EventArgs) Handles btnStripInvalidCharsREGEX.Click Dim stripped As String = String.Empty Dim sw As Stopwatch = Stopwatch.StartNew For i As Integer = 0 To 10000 stripped = Regex.Replace(_textToStrip, "[" & New String(_invalidChars) & "]", String.Empty) Next sw.Stop() lblStripInvalidCharsRegex.Text = stripped & " - in " & sw.Elapsed.TotalMilliseconds & " ms" End Sub </code></pre> The results: <img src="https://i.stack.imgur.com/SqUvd.png" alt="Performance results"> So, the for loop with string.replace outperformes all the other methods. Because of this I would make an extension function to the string object. <pre><code>Module StringExtensions <Extension()> _ Public Function ReplaceAll(ByVal InputValue As String, ByVal chars As Char(), replaceWith As Char) As String Dim ret As String = String.Empty For Each c As Char In chars ret.Replace(c, replaceWith) Next Return ret End Function </code></pre> Then you could use this function nice and readably in one line: <pre><code>_textToStrip.ReplaceAll(_invalidChars, CChar(String.Empty)) </code></pre>
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1. POReplace multiple characters in string in one line of code in VB.NET
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