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    <p>The crux of your question, I believe, is:</p> <p>"when i select any value from drop down i load some data from database that depends on this selected value, i am facing a problem whenever selection changes page will be refreshed."</p> <p>There are many ways to accomplish this, but it might require some restructuring to produce the desired effect. A relatively simple way to do this would be:</p> <p>(1) Reorganize your page as follows:</p> <pre><code>&lt;asp:DropDownList ID="ddList" CssClass="dropdown" Style="width: 200px !important;" runat="server" AutoPostBack="false"&gt; &lt;/asp:DropDownList&gt; &lt;asp:UpdatePanel ID="OuterUpdatePanel" runat="server"&gt; &lt;ContentTemplate&gt; &lt;!-- Content goes here --&gt; &lt;/ContentTemplate&gt; &lt;/asp:UpdatePanel&gt; </code></pre> <p>(2) Add script as follows:</p> <pre><code>&lt;script type="text/javascript"&gt; function handleDDLChange() { __doPostBack($('div[id$="OuterUpdatePanel"]').attr('id'), 'ddlList_Changed_Or_Anything_Else_You_Might_Want_To_Key_Off_Of'); } $('input[id$="ddlList"]').change( handleDDLChange ); &lt;/script&gt; </code></pre> <p>This is a more "old-school" approach, but it should solve your issue.</p> <p>EDIT: The following illustrates a "non-jQuery" approach, with the above idea a little more fleshed out:</p> <p>ASCX:</p> <pre><code>&lt;asp:ScriptManager runat="server" /&gt; &lt;asp:DropDownList ID="ddlList" runat="server" onchange="handleDDLChange()"&gt; &lt;asp:ListItem Text="text1" /&gt; &lt;asp:ListItem Text="text2" /&gt; &lt;/asp:DropDownList&gt; &lt;script type="text/javascript"&gt; function handleDDLChange() { __doPostBack("&lt;%= ddlList.ClientID %&gt;", "ddlList_Changed_Or_Anything_Else_You_Might_Want_To_Key_Off_Of"); } &lt;/script&gt; &lt;asp:UpdatePanel ID="UpdatePanel1" runat="server"&gt; &lt;ContentTemplate&gt; &lt;asp:Literal ID="litTest" runat="server" /&gt; &lt;/ContentTemplate&gt; &lt;/asp:UpdatePanel&gt; </code></pre> <p>Code-Behind:</p> <pre><code>protected void Page_Load(object sender, EventArgs e) { if (!Page.IsPostBack) { litTest.Text = "No postback"; } else if (Request["__EVENTARGUMENT"] == "ddlList_Changed_Or_Anything_Else_You_Might_Want_To_Key_Off_Of") { litTest.Text = string.Format("Dropdown changed: {0}", ddlList.Text); } else { litTest.Text = "Postback for some other reason... :("; } } </code></pre>
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    1. POHow to avoid page refresh after selectedindexchanged of dropdown list?
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    1. USJaime Torres
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    1. COis there any other solution without jQuery?
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    2. COI've amended my answer to include more specific code that does not rely on jQuery selectors
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