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copied!<p>Probably the best way to understand the difference is to download both examples and poke around at them yourself in Firebug, Fiddler, or similar.</p> <p>These screenshots of the network traffic for both make it pretty clear though (both of these pages do exactly the same thing, one with jQuery and one with MicrosoftAjax.js):</p> <p>Using MicrosoftAjax.js:</p> <p><img src="https://i.stack.imgur.com/2OKfW.png" alt="enter image description here"></p> <p>Using jQuery:</p> <p><img src="https://i.stack.imgur.com/uDGNd.png" alt="enter image description here"></p> <p>I'm not sure why the difference is only 90k now (but there's also an additional HTTP request too). Something to do with the version of the MSAjax.js scripts served under 3.5/4.0 vs. the 2.0 ones I was using back when I wrote that, I think.</p> <p>Even if your caching is configured correctly and those WebResource/ScriptResource scripts are cached, it's difficult to get the JS service proxy cached (<code>jsdebug</code> in the screenshot above), which you'll have to download once for every corresponding ASMX/WCF service you've referenced through the ScriptManager. Those can get fairly large too (take a look at YourService.asmx/js or YourService.asmx/jsdebug to get an idea), whereas <em>no</em> service proxy is necessary for the jQuery approach. That whole proxy exists simply to enable the <code>YourService.YourMethod()</code> calling syntax, vs. specifying the <code>YourService.asmx/YourMethod</code> path yourself. The difference in convenience is negligible; not worth the overhead IMO.</p>

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